Research References Seed Cycling Science

Effectiveness of combined seeds (pumpkin, sunflower, sesame, flaxseed): As adjacent therapy to treat polycystic ovary syndrome in females.

Rasheed, Naveed & Ahmed, Aftab & Nosheen, Farhana & Imran, Ali & Islam, Fakhar & Noreen, Rabia & Chauhan, Anamika & Shah, Mohd Asif & Ali, Yuosra. (2023). Effectiveness of combined seeds (pumpkin, sunflower, sesame, flaxseed): As adjacent therapy to treat polycystic ovary syndrome in females. Food Science & Nutrition. 10.1002/fsn3.3328.

Advantages of seed cycling diet in menstrual dysfunctions: A review based explanation.

Mahapatra, Deeptimayee & Baro, Jwngsar & Das, Mamoni. (2023). Advantages of seed cycling diet in menstrual dysfunctions: A review based explanation. 12. 931-939. 10.22271/tpi.2023.v12.i4k.19683.

Nutraceutical Intervention of Seeds in the Treatment of Poly Cystic Ovarian Syndrome; A Systematic Review

Aslam, M., Shauket, R. ., Yousaf, Z., & Tehzeeb, K. . (2021). Nutraceutical Intervention of Seeds in the Treatment of Poly Cystic Ovarian Syndrome; A Systematic Review: Nutraceutical Intervention; Seed Cycling. Pakistan BioMedical Journal, 4(2), 281–286. https://doi.org/10.54393/pbmj.v4i2.100

Role of Seed Cycling in Polycystic Ovarian Syndrome

Irfan, T. ., Seher, K. ., Rizwan, B., Fatima, S. ., & Sani, A. . (2021). Role of Seed Cycling in Polycystic OvariesSyndrome: Role of Seed Cycling in Polycystic Ovaries Syndrome. Pakistan BioMedical Journal, 4(2).https://doi.org/10.54393/pbmj.v4i2.122

Nowak DA, Snyder DC, Brown AJ, Demark-Wahnefried W. The Effect of Flaxseed Supplementation on Hormonal Levels Associated with Polycystic Ovarian Syndrome: A Case Study. Current Topics in Nutraceutical Research. 2007;5(4), 177-181.

Adlercreutz H, Hockerstedt K, Bannwart C, et al. Effect of Dietary Components, Including Lignans and Phytoestrogens, on Enterohepatic Circulation and Liver Metabolism of Estrogens and on Sex Hormone Binding Globulin (SHBG). Journal of Steroid Biochemistry. 1987; 27 (4–6): 1135–1144. doi: 10.1016/0022-4731 (87)90200-7.

Brooks JD, Ward WE, Lewis JE, et al. Supplementation with Flaxseed Alters Estrogen Metabolism in Postmenopausal Women to a Greater Extent than does Supplementation with an Equal Amount of Soy. The American Journal of Clinical Nutrition. 2004;79(2):318–325. doi:10.1093/ajcn/79.2.318.

Chen J, Stavro PM, &Thompson LU. Dietary Flaxseed Inhibits Human Breast Cancer Growth and Metastasis and Downregulates Expression of Insulin-Like Growth Factor and Epidermal Growth Factor Receptor. Nutrition and Cancer. 2002;43(2): 187-192. doi: 10.1207/s15327914nc432_9.

Haggans CJ, Hutchins AM, Olson BA, et al. Effect of Flaxseed Consumption on Urinary Estrogen Metabolites in Postmenopausal Women. Nutrition and Cancer. 1999; 33(2): 188-195. doi: 10.1207/s15327914nc330211.

Zafari M, Aghamohammady A, Tofighi M. Comparing the effect of vitamin B1 (vit. B1) and ibuberofen on the treatment of primary dysmenorhea. African Journal of Pharmacy and Pharmacology. 2011;5(7):874–878.

Gokhale LB. Curative treatment of primary (spasmodic) dysmenorrhoea. Indian Journal of Medical Research. 1996;103:227-231.

Doll H, Brown S, Thurston A, Vessey M. Pyridoxine (vitamin B6) and the premenstrual syndrome: a randomized crossover trial. The Journal of the Royal College of General Practitioners. 1989;39(326):364-368.

Kashanian M, Mazinani R, Jalalmanesh S. Pyridoxine (vitamin B6) therapy for premenstrual syndrome. International Journal of Gynecology & Obstetrics. 2006;96(1):43-44. doi:10.1016/j.ijgo.2006.09.014.

Wyatt KM, Dimmock PW, Jones PW, Obrien PMS. Efficacy of vitamin B-6 in the treatment of premenstrual syndrome: systematic review. Bmj. 1999;318(7195):1375-1381. doi:10.1136/bmj.318.7195.1375.

Bendich A. The Potential for Dietary Supplements to Reduce Premenstrual Syndrome (PMS) Symptoms. Journal of the American College of Nutrition. 2000;19(1):3-12. doi:10.1080/07315724.2000.10718907.

Goss PE, Li T, Theriault M, Pinto S, Thompson LU. Effects of Dietary Flaxseed in Women with Cyclical Mastalgia. Breast Cancer Research and Treatment. 2000; 64(1):49.

Adibmoghaddam E, Jaafarnejad F, Emami SA, Saki A. Compare the Effect of Flaxseed, Evening Primrose Oil and Vitamin E on Duration of Periodic Breast Pain. Journal of Education and Health Promotion. 2017; 6(1):85. doi: 10.4103/jehp.jehp_83_16.

Mirghafourvand M, Mohammad-Alizadeh-Charandabi S, Ahmadpour P, Javadzadeh Y. Effects of Vitex Agnus and Flaxseed on Cyclic Mastalgia: A Randomized Controlled Trial. Complementary Therapies in Medicine. 2016;24:90-95. doi: 10.1016/j.ctim.2015.12.009.

Vaziri F, Lari MZ, Dehaghani, AS, et al. Comparing the Effects of Dietary Flaxseed and Omega-3 Fatty Acids Supplement on Cyclical Mastalgia in Iranian Women: A Randomized Clinical Trial. International Journal of Family Medicine. 2014;2014: 1-7. doi: 10.1155/2014/174532.

Fatima Farzana K, et al. Effects of Flax Seeds Supplementation in Polycystic Ovarian Syndrome. International Journal of Pharmaceutical Sciences Review and Research. 2015;31(1), 113–119.

Fathizadeh N, Ebrahimi E, Valiani M, Tavakoli N, Yar MH. Evaluating the Effect of Magnesium and Magnesium Plus Vitamin B6 Supplement on the Severity of Premenstrual Syndrome. Iranian Journal of Nursing and Midwifery Research. 2010;15(1):401-405.

London RS, Bradley L, Chiamori NY. Effect of a nutritional supplement on premenstrual symptomatology in women with premenstrual syndrome: a double-blind longitudinal study. Journal of the American College of Nutrition. 1991;10(5): 494-499. doi: 10.1080/07315724.1991.10718176.

Souza MCD, Walker AF, Robinson P A, & Bolland K. A synergistic effect of a daily supplement for 1 month of 200 mg magnesium plus 50 mg Vitamin B₆ for the relief of anxiety-related premenstrual symptoms: A randomized, double-blind, crossover study. Journal of Women's Health & Gender-Based Medicine. 2000;9(2):131-139. doi:10.1089/152460900318623.

Walker AF, Souza MCD, Vickers MF, Abeyasekera S, Collins ML, and Trinca LA. Magnesium supplementation alleviaes premenstrual symptoms of fluid retention. Journal of Women's Health. 1998;7(9):1157-1165. doi: 10.1089/jwh.1998.7.1157.

Facchinetti F, et al. Oral magnesium successfully relieves premenstrual mood changes. Obstetrics And Gynecology. 1991; 78(2): 177–181.

Quaranta S, Buscaglia MA, Meroni MG, Colombo E, Cella S. Pilot study of the efficacy and safety of a modified-release magnesium 250mg tablet (sincromag??) for the treatment of premenstrual syndrome. Clinical Drug Investigation. 2007;27(1):51-58. doi:10.2165/00044011-200727010-00004.

Facchinetti F, Sances G, Borella P, Genazzani AR, Nappi G. Magnesium Prophylaxis of Menstrual Migraine: Effects on Intracellular Magnesium. Headache: The Journal of Head and Face Pain. 1991;31(5):298–301. doi: 10.1111/j.1526-4610.1991.hed3105298.x.

Gokhale LB. Curative treatment of primary (spasmodic) dysmenorrhoea. Indian Journal of Medical Research. 1996;103:227-231.

Abdollahifard S, Maddahfar M. The effects of vitamin B1 on ameliorating of mental symptoms of the premenstrual syndrome. European Psychiatry. 2016;33:s335. doi:10.1016/j.eurpsy.2016.01.745.

Abdollahifard S, Maddahfar M. The effects of vitamin B1 on ameliorating of depression related to the premenstrual syndrome. European Psychiatry. 2016;33:s174-s175. doi:10.1016/j.eurpsy.2016.01.291.

Chocano-Bedoya PO, Manson JE, Hankinson SE, et al. Dietary B vitamin intake and incident premenstrual syndrome. The American Journal of Clinical Nutrition. 2011;93(5):1080-1086. doi:10.3945/ajcn.110.009530.

Siahbazi S, Behboudi-Gandevani S, Moghaddam-Banaem L, Montazeri A. Effect of zinc sulfate supplementation on premenstrual syndrome and health-related quality of life: Clinical randomized controlled trial. Journal of Obstetrics and Gynaecology Research. 2017;43(5): 887–894. doi: 10.1111/jog.13299.

Chuong CJ, Dawson EB. Zinc and copper levels in premenstrual syndrome.* Fertility And Sterility. 1994;62(2):313–320. doi:10.1016/s0015-0282(16)56884-8.

Sangestani G, et al. The Positive Effects of Zinc Supplements on the Improvement of Primary Dysmenorrhea and Premenstrual Symptoms: A Double-blind, Randomized, Controlled Trial. Journal of Midwifery & Reproductive Health. 2015;3(3):378-384.

Eby GA. Zinc treatment prevents dysmenorrhea. Medical hypotheses. 2007;69(2):297-301. doi: 10.1016/j.mehy.2006.12.009.

Kelly RW, Abel MH. Copper and Zinc Inhibit the Metabolism of Prostaglandin by the Human Uterus. Biology of Reproduction. 1983;28(4):883–889. doi:10.1095/biolreprod28.4.883.

Prasad AS. Zinc is an Antioxidant and Anti-Inflammatory Agent: Its Role in Human Health. Frontiers in Nutrition. 2014;1. doi:10.3389/fnut.2014.00014.

Kashefi F, Khajehei M, Tabatabaeichehr M, Alavinia M, Asili J. Comparison of the effect of ginger and zinc sulfate on primary dysmenorrhea: A placebo-controlled randomized trial. Pain Management Nursing. 2014;15(4):826-833. doi: 10.1016/j.pmn.2013.09.001.

Zekavat OR, Karimi MY, Amanat A, Alipour F. A randomised controlled trial of oral zinc sulphate for primary dysmenorrhoea in adolescent females. The Australian & New Zealand Journal of Obstetrics & Gynaecology. 2015;55(4) :369-73. doi:10.1111/ajo.12367.

Teimoori B, Ghasemi M, Hoseini ZSA, Razavi M. The Efficacy of Zinc Administration in the Treatment of Primary Dysmenorrhea. Oman Medical Journal. 2016;31(2):107-111. doi:10.5001/omj.2016.21.

Yavari M, Rouholamin S, Tansaz M, Bioos S, Esmaeili S.. Sesame a Treatment of Menstrual Bleeding Cessation in Iranian Traditional Medicine: Results From a Pilot Study. Shiraz E-Medical Journal. 2014;15(3). doi:10.17795/semj21893.